Potential of Fucoidan From Brown Seaweeds (Sargassum sp.) as Innovation Therapy on Breast Cancer
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چکیده
منابع مشابه
Antitumor active fucoidan from the brown seaweed, umitoranoo (Sargassum thunbergii).
Neutral and acidic polysaccharides and their protein complexes were fractionated and purified from the brown seaweed umitoranoo (Sargassum thunbergii) by fractional extraction, iron-exchange chromatography, and gel filtration. Thirty-one polysaccharide fractions were obtained and tested for antitumor activity in mice with Ehrlich carcinoma transplanted i.p. Two of the fractions, GIV-A ([alpha]2...
متن کاملChemical composition antioxidant and antimicrobial activities of fucoidan extracted from two species of brown seaweeds (Sargassum ilicifolium and S.angustifolium) around Qeshm Island
The chemical compositions, antioxidant and antimicrobial properties of fucoidan extracted from Sargassum ilicifolium and S.angustifolium were investigated. The results showed that these seaweeds were characterized by an acceptable level of minerals and proteins. The fatty acid profile was dominated by the palmitic acid, which represents about 37.44±0.01% and 23.05±0.01% of the total fatty acids...
متن کاملChemical composition antioxidant and antimicrobial activities of fucoidan extracted from two species of brown seaweeds(Sargassum ilicifolium and S.angustifolium) around Qeshm Island
The chemical compositions, antioxidant and antimicrobial properties of fucoidan extracted from Sargassum ilicifolium and S.angustifolium were investigated. The results showed that these seaweeds were characterized by an acceptable level of minerals and proteins. The fatty acid profile was dominated by the palmitic acid, which represents about 37.44±0.01% and 23.05±0.01% of the...
متن کاملStructural Characteristics and Anticancer Activity of Fucoidan from the Brown Alga Sargassum mcclurei
Three different fucoidan fractions were isolated and purified from the brown alga, Sargassum mcclurei. The SmF1 and SmF2 fucoidans are sulfated heteropolysaccharides that contain fucose, galactose, mannose, xylose and glucose. The SmF3 fucoidan is highly sulfated (35%) galactofucan, and the main chain of the polysaccharide contains a →3)-α-L-Fucp(2,4SO₃⁻)-(1→3)-α-L-Fucp(2,4SO₃⁻)-(1→ motif with ...
متن کاملIn Silico Analysis of the Potential of the Active Compounds Fucoidan and Alginate Derived from Sargassum Sp. as Inhibitors of COX-1 and COX-2
INTRODUCTION The enzyme cyclooxygenase (COX) is an enzyme that catalyzes the formation of one of the mediators of inflammation, the prostaglandins. Inhibition of COX allegedly can improve inflammation-induced pathological conditions. AIM The purpose of the present study was to evaluate the potential of Sargassum sp. components, Fucoidan and alginate, as COX inhibitors. MATERIAL AND METHODS ...
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ژورنال
عنوان ژورنال: Journal of Medicine & Health
سال: 2019
ISSN: 2442-5257
DOI: 10.28932/jmh.v2i3.1235